Who is President Trump’s new chief of staff, Susie Wiles?
She is said to be the main reason for Donald Trump’s political comeback. Here’s what you need to know about Susie Wiles.
President Donald Trump announced on Monday, March 16, that his chief of staff, Susie Wiles, has been diagnosed with breast cancer.
The president shared the news in a post on social platform Truth Social, saying that Wiles, the first woman to serve as White House chief of staff, was suffering from “early stage breast cancer” but would continue in her role while undergoing treatment.
“Rather than wait,[she]decided to take on this challenge right away. She has an amazing medical team and her prognosis is good,” Trump’s post read. “During her treatment, she will be spending virtually all of her time at the White House.”
Wiles is one of President Trump’s closest aides and has been involved in his campaign since 2015. Previously, he worked as a scheduler under Chief of Staff James Baker on President Ronald Reagan’s 1980 campaign and under Vice President Dan Quayle in the George H.W. Bush administration. She has led several other campaigns, including Ron DeSantis’ candidacy for Florida governor in 2018.
Wiles, whom Trump called “one of my closest and most important advisers” in social media posts, has been in the news since being appointed early in the second administration.
She was part of the February 2025 prisoner exchange between Russia and the United States in which Russian entrepreneur Alexander Vinnik and American schoolteacher Mark Vogel were exchanged. She also became a board member of the John F. Kennedy Center for the Performing Arts in March 2025 after President Trump removed incumbent members and replaced them with supporters.
In December 2025, she was thrust back into the spotlight when she appeared in a Vanity Fair spread for her unflinching photos. She told journalist Chris Whipple that Trump is an “alcoholic personality,” that Vice President J.D. Vance has been a “conspiracy theorist for 10 years,” and that Attorney General Pam Bondi “completely negates” the initial release of the Epstein files.
Wiles later called the article “a disingenuously constructed hit piece.”
“President Trump has never had a greater and more loyal advisor than Susie,” White House press secretary Caroline Levitt said at the time. “The entire government is grateful for her steady leadership and is fully united behind her.”
This story has been updated to add new information.

